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| Giancarlo Esposito | Hypnos | |
| Dave Foley | Herb | |
| Bridget Fonda | Dr. Julie McElroy | |
| Christopher Franciosa | ||
| Brendan Fraser | Stu Miley | |
| Whoopi Goldberg | Death | |
| Chris Kattan | ||
| Rose McGowan | Miss Kitty | |
| Megan Mullally | Kimmy Miley | |
| Mary Pierce | ||
| John Turturro | Monkeybone | |
| Lisa Zane | Medusa | |
| Amy Higgins | Clarissa |
| Director |
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| Producer | Chris Columbus
Michael Barnathan |
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| Writer | Sam Hamm
Kaja Blackley |
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| Cinematography | Andrew Dunn
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| Musician | Anne Dudley
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After a car crash sends repressed cartoonist Stu Miley (Fraser) into a coma, he and the mischievous Monkeybone, his hilariously horny alter-ego, wake up in a wacked-out waystation for lost souls. When Monkeybone takes over Stu's body and escapes to wreak havoc on the real world, Stu has to find a way to stop him before his sister pulls the plug on reality forever! |
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