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| Patricia Arquette | Frankie Paige | |
| Gabriel Byrne | Father Andrew Kiernan | |
| Nia Long | Donna Chadway | |
| Jonathan Pryce | Cardinal Daniel Houseman | |
| Enrico Colantoni | Father Dario | |
| Ann Cusack | Dr. Reston | |
| Portia De Rossi | Jennifer Kelliho | |
| Tom Fahn | MTA Man | |
| Lydia Hazan | Attending Nurse | |
| Tom Hodges | ER Nurse | |
| Thomas Kopache | Father Durning | |
| Dick Latessa | Father Gianni Delmonico | |
| Duke Moosekian | Dr. Eckworth | |
| Patrick Muldoon | Steven | |
| Mariah Nunn | Sister Angela |
| Director |
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| Producer | Frank Mancuso Jr.
Vikki Williams |
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| Writer | Tom Lazarus
Rick Ramage |
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| Cinematography | Jeffrey L. Kimball
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| Musician | Elia Cmiral
Billy Corgan |
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A priest from the Vatican is sent in to investigate claims that a town in Brazil has a church where statues bleed from the eyes. Meanwhile, a young woman in the U.S. begins to show signs of stigmata. |
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